From the airport
From the Berlin Brandenburg Airport BER: take either the FEX Airport express train RE7 or RB14 regional train to Friedrichstrasse station. Alternatively the S9 S-Bahn also goes to this station. From there switch to the U6 and exit at "Stadtmitte". The hotel is on the right side at the Leipziger Straße. It's a 30 minute trip.
Taxi: It's a 30 - 40 minute trip and is around €50.
You can choose between a single ticket (€3.80), a day ticket (€10.60) or a ticket for a week (€44.60). Within the ticket price, you can take the train and the bus in sector A and B.